University of Brasília logoFaculty of Medicine | University of Brasília
Contact: laboratorioimunologi@unb.br | licfmunb@gmail.com
Established in 1981 | Faculty of Medicine

Laboratory of Cellular ImmunologyFaculty of Medicine | University of Brasília

The Laboratory of Cellular Immunology, University of Brasília, is one of Brazil's traditional research centers in immunology, with more than four decades of uninterrupted activity in infectious, inflammatory, autoimmune and immunopharmacological investigations.

1981Year of establishment
40+Years of activity
65+Dissertations and theses
13Flow cytometry channels
Graduation practical activity at the laboratory
Cellular and molecular immunology applied to public health challenges and academic training.

Tradition, science and innovation in immunology

The Laboratory of Cellular Immunology has consolidated itself as a national reference in the investigation of immunological mechanisms underlying infectious, inflammatory and autoimmune diseases.

Throughout its history, the laboratory has played a strategic role in scientific production and in the training of highly qualified researchers, supervising master's dissertations, doctoral theses and undergraduate research projects.

Institutionally, LIC/FM is part of the portfolio of multi-user laboratories coordinated by the Dean's Office for Research and Innovation at the University of Brasília and is registered in the National Research Infrastructure Platform of the Ministry of Science, Technology and Innovation.

Principles that guide the laboratory

LIC/FM combines scientific excellence, academic legacy, mentorship and social responsibility in the development of research and training activities.

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Scientific Excellence

Commitment to methodological rigor, reproducibility and innovation in the investigation of immunological mechanisms.

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Tradition and Legacy

A trajectory initiated in 1981 at the Faculty of Medicine of UnB, maintaining consistent scientific output and national relevance.

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Academic Training

Dedication to undergraduate and graduate education, promoting the solid training of qualified researchers.

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Ethics and Responsibility

Research ethics, academic integrity and commitment to knowledge that generates real benefits for public health.

Modern multi-user research infrastructure

LIC/FM encompasses diversified infrastructure for cellular and molecular immunology, including flow cytometry, cell culture, biosafety cabinets, microscopy, centrifugation, luminometry, spectrophotometry and water purification systems.

Cell culture room

Cell culture room

Dedicated environment for mammalian cell culture and cellular immunology protocols.

Sample processing laboratory

Sample processing

Support for sample processing, experimental assays and laboratory routines.

Cell culture biosafety cabinet

Biosafety cabinet

NB2 biosafety cabinets for cell culture and laboratory experimental routines.

BD Biosciences LSRFortessa flow cytometer

Flow cytometry

BD FACS Fortessa LSR II with blue, red and violet lasers and 13 detection channels.

Inverted microscope

Inverted microscopy

Microscopy systems for cellular observation, imaging and experimental monitoring.

CO2 incubators

CO₂ incubators

Equipment for controlled cell culture conditions and research protocols.

Ultracentrifuge

Ultracentrifuge

Equipment for high-speed processing of samples in immunology research.

Microtome

Microtome

Infrastructure for sample preparation and histological support routines.

Spectrophotometer and luminometer station

Analytical platform

Luminometry, spectrophotometry and support systems for quantitative assays.

Legacy and foundation of LIC/FM

Dr. Carlos Eduardo Tosta da Silva

Dr. Carlos Eduardo Tosta da Silva

Founder | Professor Emeritus

Distinguished academic and researcher in immunology, tropical medicine and parasitology. His career integrated research, teaching and extension, consolidating UnB as a center of excellence in biomedical sciences and tropical disease research.

His pioneering research lines focused on the immunology of parasitic diseases, especially malaria, leishmaniasis and Chagas disease.

Dr. Maria Imaculada Muniz Junqueira

Dr. Maria Imaculada Muniz Junqueira

Founder | Professor Emerita

Nationally recognized researcher in cellular and molecular immunology. She played a decisive role in consolidating LIC/FM as a multi-user facility and contributed to research on malaria, leishmaniasis, Zika virus and other tropical diseases.

Her legacy includes scientific production, academic training and strengthening of institutional partnerships.

Researchers and technical staff

The team brings together faculty members, PhD managers and technical staff with expertise in immunology, microbiology, tropical medicine, molecular pathology and cell culture.

PhD Managers

Dr. Tatiana Karla dos Santos Borges

Tatiana Karla dos Santos Borges

Assistant Professor | Medical Immunology

Assistant Professor at the Faculty of Medicine, University of Brasília. Her trajectory focuses on immunology, infectious diseases, tropical medicine, molecular pathology and advanced cell culture techniques.

Dr. Pedro Henrique Miranda Bürgel

Pedro Henrique Miranda Bürgel

Assistant Professor | Microbiology and Immunology

Assistant Professor specializing in medical microbiology, immunology and host-pathogen interactions, with research focused on fungal pathogenesis, macrophage biology and immunometabolic regulation.

Technical Staff

Dr. Shirley Claudino Pereira Couto

Shirley Claudino Pereira Couto

Technical Staff

Holds a degree in Biological Sciences, a master's degree and a PhD in Tropical Medicine from the University of Brasília. Her doctoral research focused on NF-κB signaling pathways and inflammatory responses in cerebral malaria models.

Dr. Mariangela Souza de Oliveira

Mariangela Souza de Oliveira

Technical Staff

Holds a master's degree in Tropical Medicine and a PhD in Molecular Pathology from the University of Brasília, with research on immunological mechanisms and host-parasite interactions in Zika virus infection.

Scientific lines of investigation

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Tropical and Infectious Diseases

Study of immunopathological processes in leishmaniasis, malaria and other infectious diseases, focusing on host-pathogen interactions.

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Cell Culture and Molecular Pathology

Application of advanced cell culture methodologies to analyze immunological responses and intracellular signaling pathways.

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Bioactive Compounds and Nanotechnology

Evaluation of natural extracts and nanostructured systems for therapeutic applications in health, oncology and immunomodulation.

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Aesthetic Health and Clinical Immunology

Research on immunological aspects of aesthetic interventions and their impact on tissue regeneration and inflammatory modulation.

Current academic training and research projects

MSc Atvaldo Fernandes Ribeiro JuniorPhD candidate in Tropical Medicine. Thesis: protective and anti-inflammatory effects of Atazanavir in cell cultures stimulated with the SARS-CoV-2 Spike S1 protein.
MSc Andréia Cristina Gonçalves CascaesPhD candidate in Tropical Medicine. Thesis on immunomodulatory effects of anacardic acid in monocytes stimulated by Plasmodium-infected erythrocytes.
Glauco de Oliveira MacedoMSc candidate in Tropical Medicine. Research on anti-inflammatory and cytoprotective effects of Ocelatin PT-4 and curcumin on human monocytes infected with Zika virus.
Marcela de Castro TrajanoMSc candidate in Medical Sciences. Research on anti-inflammatory and antioxidant action of ozone therapy in fibroblasts, keratinocytes and macrophages.
João Paulo dos Santos PiresMSc candidate in Medical Sciences. Research on anti-inflammatory, antiviral and cytoprotective action of curcumin in human microglia exposed to Zika virus.
Catarina Barreto Chaves NunesUndergraduate scientific student. Project: activation of the NFκB pathway in experimental malaria.

Scientific production

Selected articles, dissertations and theses associated with the laboratory and its research lines.

Article | 2026Saturated anacardic acid shows promise as adjuvant therapy for preventing severe malaria via attenuation of inflammatory response by modulation of the NF-κB pathway.
Gontijo ACGC, et al. Acta Tropica.
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Article | 2026LC3-associated phagocytosis in macrophage responses to Paracoccidioides spp.
Oliveira Junior GP, et al. Memórias do Instituto Oswaldo Cruz.
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Article | 2026Leishmanicidal and Immunomodulatory Effects of Ocellatin-PT4 and Ocellatin-PT6 on Amastigotes of Leishmania amazonensis.
Oliveira MGC, et al. Future Pharmacology.
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Article | 2025Immunomodulatory and behavioral effects of ayahuasca and N,N-dimethyltryptamine in a rat model of lipopolysaccharide-induced depression.
Nascimento Sousa D, et al. Metabolic Brain Disease.
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Dissertation | 2021Effect of curcumin in the treatment of microglia infected with Zika virus.
Albuquerque LFF. University of Brasília, Faculty of Medicine, Graduate Program in Tropical Medicine.
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Dissertation | 2006Influence of pentoxifylline on murine infection by Plasmodium berghei ANKA in models susceptible or resistant to cerebral malaria.
Borges TKS. Graduate Program in Molecular Pathology.
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Thesis | 2013Mechanisms of inflammatory response in murine models of Plasmodium berghei ANKA, susceptible or resistant to cerebral malaria.
Borges TKS. Graduate Program in Molecular Pathology.
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Laboratory of Cellular Immunology

Faculty of Medicine, Darcy Ribeiro Campus, University of Brasília.

Contact information

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Instagram:
@licfmunb
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Address:
Sala BT 68/17, corredor central
Faculdade de Medicina, Campus Darcy Ribeiro
Área 1, Universidade de Brasília
Asa Norte, Brasília, Distrito Federal
CEP: 70910-900